ACCIDENTAL REVACCINATION.

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Revaccination and Duration of Protection

Pneumococcal polysaccharide vaccine induces an initial rise in ELISA antibody levels, which then decline over time and in older adults antibody levels measured 4 to 7 years post-vaccination tend to approximate pre-vaccination baseline levels (1-5). The clinical significance of this decline is not well defined, as immune correlates of protection for pneumococcal vaccine in adults have not been e...

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Frequency of Revaccination against Smallpox

extending the time for revaccination beyond 10 years may be based on insufficient and conflicting evidence of persistence of immunity (1,2). The evidence that cellmediated immunity and neutralizing antibody persist after one vaccination is conflicting (2–5). This residual immunity is often low, and its protective activity in vivo is unclear. Similarly, in vivo reports of durable immunity to sma...

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Prevention of Smallpox by Vaccination and Revaccination

PREVENTION OF SMALLPOX BY VACCINATION AND REVACCINATION Sir,?In reference to the paper entitled ' Prevention of Smallpox by Vaccination and Revaccination' published in the May 1945 issue of your esteemed journal I beg to further supplement my observations by offering the following hypothesis regarding the conception of immunity and its fluctuations, conferred by smallpox vaccination and revacci...

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[BCG revaccination in schoolchildren: a pioneer study].

* Professor Adjunto do Departamento de Pediatria da Faculdade de Medicina da Universidade Federal do Rio de Janeiro (UFRJ). Presidente do Departamento Científico de Pneumologia da SBP. O primeiro de julho é o Dia da Vacina BCG. O fato de existir uma data comemorativa para a vacina demonstra a sua importância na história da humanidade. Essa vacina encerra inúmeras controvérsias desde que foi emp...

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Generalized Vaccinia 2 Days after Smallpox Revaccination

To the Editor: Hospital and public health personnel are currently receiving smallpox vaccination in a national effort to increase preparedness for a possible deliberate release of smallpox (1). Generalized vaccinia (GV) is a typically self-limited adverse event following vaccination (incidence 23.4–238.2 cases per million primary vaccinees and 1.2–10.8 cases per million revaccinees) (2,3). We r...

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ژورنال

عنوان ژورنال: The Lancet

سال: 1904

ISSN: 0140-6736

DOI: 10.1016/s0140-6736(00)30487-1